| Cat.No.: | EAb-2026 |
| Antibody Type: | Polyclonal |
| Immunogen: | This CTBP antibody was raised against a peptide within the C-terminal region of human CTBP. |
| Host: | Rabbit |
| Isotype: | Serum |
| Molecular Weight: | 50 kDa |
| Purification: | None |
| Appearance: | Liquid |
| Formulation: | Rabbit serum containing 30% glycerol and 0.035% sodium azide. |
| Applications: | WB: 1:500 - 1:2,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | CTBP (C-terminal Binding Protein, CTBP1) is a transcriptional repressor that was originally identified by virtue of its ability to bind the C-terminus of E1A proteins. CTBP serves as a co-repressor for a number of DNA binding transcription factors. CTBP is part of a variety of co-repressor complexes, many of which include HDAC proteins. CTBP also interacts with vertebrate Polycomb proteins including Pc2, suggesting that repression of many CTBP-regulated genes also involves recruitment of the Polycomb complex. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0168 | Human CTDSP1 Knockout Cell Line 26bp deletion | Inquiry |
| CL-0195 | Human CTDSPL Knockout Cell Line 1bp insertion | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0169 | Recombinant Human CTSL1 Cell Lysate | Inquiry |
| EL-0204 | Recombinant Human CTCFL 293 Cell Lysate | Inquiry |
| ◆ Antibodies | ||
| EAb-0849 | CTCF Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| CTBP | CTBP2 | CTCF | CTCFL |
| CTDSP1 | CTDSPL | CtIP | ctnnb1 |
| CTSL1 | |||
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