| Cat.No.: | PE-1370 |
| Product Name: | Recombinant Human KDM4D, FLAG-tagged |
| Product Overview: | Recombinant Human KDM4D (accession number NP_060509.2) was expressed in Sf9 cells and contains an N-terminal FLAG tag with an observed molecular weight of 63.2 kDa. |
| Description: | KDM4D (lysine (K)-specific demethylase 4D), also known as JMJD2D (Jumonji Domain Containing 2D) is a protein that functions as a histone demethylase that preferentially demethylates di- and trimethylated lysine 9 residues of histone H3, while it has no activity on monomethylated H3K9 residues. |
| Applications: | Enzyme kinetics, inhibitor screening, and selectivity profiling. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Species: | Human |
| Formulation: | 25 mM HEPES, pH 7.5, 150 mM NaCl and 5% glycerol. |
| Tag: | FLAG |
| Activity: | H3K9me3 demethylase. |
| Expression System: | Sf9 Insect Cells |
| Concentrations: | 0.8 mg/ml |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | KDM4D lysine (K)-specific demethylase 4D [ Homo sapiens ] |
| Gene ID NCBI: | 55693 |
| Synonyms: | KDM4D; lysine (K)-specific demethylase 4D; JMJD2D, jumonji domain containing 2D; lysine-specific demethylase 4D; FLJ10251; jumonji domain containing 2D; jumonji domain-containing protein 2D; jmjC domain-containing histone demethylation protein 3D; JMJD2D; MGC141909; |
| mRNA Refseq: | NM_018039 |
| Protein Refseq: | NP_060509 |
| MIM: | 609766 |
| UniProt ID: | Q6B0I6 |
| Chromosome Location: | 11q21 |
| Function: | metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0015 | Human KDM5B Knockout Cell Line 14bp deletion | Inquiry |
| CL-0087 | Human KDM1A Knockout Cell Line 10bp deletion | Inquiry |
| CL-0088 | Human KDM1B Knockout Cell Line 13bp deletion | Inquiry |
| CL-0089 | Human KDM2B Knockout Cell Line 14bp deletion | Inquiry |
| ◆ Antibodies | ||
| EAb-0071 | KDM1B Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| KDM1 | KDM1A | KDM1B | KDM2 |
| KDM2A | KDM2B | KDM3A | KDM3B |
| KDM4 | KDM4A | KDM4B | KDM4C |
| KDM4D | KDM4E | KDM5 | KDM5A |
| KDM5B | KDM5C | KDM5D | KDM6A More > |
| KDM6B | KDM6C | KDM7 | KDM7A |
| KDM7B | KDM8 | ||
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