| Cat.No.: | PE-1305 |
| Product Name: | Recombinant Human K(lysine) Acetyltransferase 5, GST-tagged |
| Product Overview: | Recombinant full-length human KAT5 (TIP60) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
| Description: | KAT5 or K (lysine) acetyltransferase 5 is a signaling protein that belongs to the MYST family of histone acetyl transferases (HATs). KAT5 was originally isolated as an HIV-1 TAT-interactive protein that plays an important role in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. KAT5 protein is a histone acetylase that is involved in DNA repair and apoptosis and plays an important role in signal transduction. KAT5 acts as a cofactor of TAT that is involved in the regulation of HIV gene expression. KAT5 is also a co-regulator of transcription factors that either promote or suppress tumorigenesis. |
| Applications: | Western Blot |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 88 kDa |
| Purity: | > 90 % |
| Species: | Human |
| Formulation: | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0,25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
| Tag: | GST |
| Expression System: | Sf9 Insect Cells |
| Protein Length: | Full length |
| Concentrations: | 0.1 ug/ul |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | KAT5 K(lysine) acetyltransferase 5 [ Homo sapiens ] |
| Gene ID NCBI: | 10524 |
| Official Symbol: | KAT5 |
| Synonyms: | KAT5; K(lysine) acetyltransferase 5; TIP; ESA1; PLIP; TIP60; cPLA2; HTATIP; HTATIP1; histone acetyltransferase KAT5; OTTHUMP00000233811; OTTHUMP00000233812; OTTHUMP00000233813; OTTHUMP00000233848; K-acetyltransferase 5; cPLA2 interacting protein; lysine acetyltransferase 5; cPLA(2)-interacting protein; 60 kDa Tat-interactive protein; Tat interacting protein, 60kDa; histone acetyltransferase HTATIP; HIV-1 Tat interactive protein, 60kDa; NP_001193762.1; NP_006379.2; NP_874368.1; NP_874369.1; EC 2.3.1.48; Histone acetyltransferase HTATIP; HIV-1 Tat interactive protein, 60kDa |
| mRNA Refseq: | NM_006388 |
| Protein Refseq: | NP_006379 |
| MIM: | 601409 |
| UniProt ID: | Q92993 |
| Chromosome Location: | 11q13 |
| Function: | androgen receptor binding; contributes_to histone acetyltransferase activity; metal ion binding; protein binding; repressing transcription factor binding; transcription coactivator activity; transferase activity, transferring acyl groups other than amino-acyl groups |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0073 | Anacardic Acid | Inquiry |
| ◆ Antibodies | ||
| EAb-0073 | KAT8 Polyclonal Antibody | Inquiry |
| ◆ Cell Lines | ||
| CL-0083 | Human KAT2A Knockout Cell Line 1bp insertion | Inquiry |
| CL-0085 | Human KAT2B Knockout Cell Line 31bp deletion | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0159 | Recombinant Human MYST2 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| Kaiso | KANSL2 | KAP1 | KAT13A |
| KAT13D | KAT2A | KAT2B | KAT4 |
| KAT5 | KAT6A | KAT6B | KAT7 |
| KAT8 | KAT9 | ||
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