| Cat.No.: | PE-1231 |
| Product Name: | Recombinant Human RAC3, His-tagged |
| Product Overview: | Recombinant full-length human RAC3 Protein was expressed in E. coli cells using an N-terminal His tag. |
| Description: | RAC3 is a GTPase which belongs to the RHO family of small GTP-binding proteins that regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. RAC3 is primarily expressed in brain and is proposed to play a specific function in neuronal cells. Depletion of RAC3 induces stronger cell adhesion and dramatically increases the outgrowth of neurite-like protrusions whereas overexpression of RAC3 results in a contractile round morphology. RAC3 can exert its function through negatively affecting integrin-mediated cell-matrix adhesions. RAC3 shares with RAC1 the ability to interfere with cadherin-mediated adhesion. |
| Applications: | Kinase Assay, Western Blot |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | ~24 kDa |
| Purity: | >95% |
| Species: | Human |
| Formulation: | Recombinant protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol. |
| Tag: | His |
| Expression System: | E. coli |
| Protein Length: | Full length |
| Concentrations: | 0.2 μg/μl |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | NCOA3 nuclear receptor coactivator 3 [ Homo sapiens ] |
| Gene ID NCBI: | 8202 |
| Synonyms: | NCOA3; nuclear receptor coactivator 3; ACTR; AIB1; bHLHe42; CAGH16; KAT13B; p/CIP; RAC3; receptor associated coactivator 3; SRC 3; SRC3; thyroid hormone receptor activator molecule 1; TNRC16; TRAM 1; CBP-interacting protein; receptor-associated coactivator 3; amplified in breast cancer 1 protein; steroid receptor coactivator protein 3; class E basic helix-loop-helix protein 42; pCIP; AIB-1; CTG26; SRC-3; TNRC14; TRAM-1; MGC141848; |
| mRNA Refseq: | NM_001174087 |
| Protein Refseq: | NP_001167558 |
| MIM: | 601937 |
| UniProt ID: | Q9Y6Q9 |
| Chromosome Location: | 20q12 |
| Function: | androgen receptor binding; chromatin binding; estrogen receptor binding; histone acetyltransferase activity; ligand-dependent nuclear receptor binding; ligand-dependent nuclear receptor transcription coactivator activity; nuclear hormone receptor binding; protein N-terminus binding; protein binding; signal transducer activity; thyroid hormone receptor binding; transcription coactivator activity; transcription coactivator activity; transcription coactivator activity; transferase activity, transferring acyl groups; |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0044 | RARA Polyclonal Antibody | Inquiry |
| EAb-0356 | RAD54L2 Polyclonal Antibody | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0316 | TZ9 | Inquiry |
| ◆ Cell Lines | ||
| CL-0390 | Human RAD52 Knockout Cell Line 2bp insertion | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-1231 | Recombinant Human RAC3, His-tagged | Inquiry |
| Related Gene / Proteins | |||
| RAC3 | Rad21 | RAD52 | RAD54L2 |
| Rad6 | Rad6B | RAG1 | RAG2 |
| RALY | RALYL | RANBP2 | RAP1 |
| RAR-β | RAR-γ | RARA | |
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