| Cat.No.: | PE-1220 |
| Product Overview: | Recombinant full-length human KAT7 (MYST2) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
| Description: | KAT7 or K (lysine) acetyltransferase 5 is a signaling protein that belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein which play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and non-histone proteins. KAT7 acts as a transcriptional inhibitor and inhibited AR-mediated transactivation of reporter constructs in CV-1 and PC-3 cells. KAT7 is part of a multisubunit complex that can acetylate histones H3 and H4. |
| Applications: | Western Blot |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 110 kDa |
| Purity: | > 85 % |
| Species: | Human |
| Formulation: | Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 25% glycerol. |
| Tag: | GST |
| Expression System: | Sf9 Insect Cells |
| Protein Length: | Full-length |
| Concentrations: | 0.1 ug/ul |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | KAT7 K(lysine) acetyltransferase 7 [ Homo sapiens ] |
| Gene ID NCBI: | 11143 |
| Official Symbol: | KAT7 |
| Synonyms: | KAT7; HBO1; HBOA; MYST2; MYST histone acetyltransferase 2; Histone acetyltransferase binding to ORC1; MYST-2; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2; OTTHUMP00000220716; OTTHUMP00000220718; histone acetyltransferase MYST2; EC2.3.1.48 |
| mRNA Refseq: | NM_007067 |
| Protein Refseq: | NP_008998 |
| MIM: | 609880 |
| UniProt ID: | O95251 |
| Chromosome Location: | 17q21.32 |
| Function: | histone acetyltransferase activity; metal ion binding; protein binding; sequence-specific DNA binding transcription factor activity; transferase activity, transferring acyl groups other than aminoacyl groups; zinc ion binding |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0073 | Anacardic Acid | Inquiry |
| ◆ Antibodies | ||
| EAb-0073 | KAT8 Polyclonal Antibody | Inquiry |
| ◆ Cell Lines | ||
| CL-0083 | Human KAT2A Knockout Cell Line 1bp insertion | Inquiry |
| CL-0085 | Human KAT2B Knockout Cell Line 31bp deletion | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0159 | Recombinant Human MYST2 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| Kaiso | KANSL2 | KAP1 | KAT13A |
| KAT13D | KAT2A | KAT2B | KAT4 |
| KAT5 | KAT6A | KAT6B | KAT7 |
| KAT8 | KAT9 | ||
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