| Cat.No.: | PE-1110 |
| Product Name: | Recombinant Human O-6-methylguanine-DNA Methyltransferase, T7-tagged |
| Product Overview: | Recombinant MGMT protein, fused to T7-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques, 21646Da (207aa). |
| Description: | Methylated-DNA-protein-cysteine methyltransferase is an enzyme that in humans is encoded by the MGMT gene. |
| Applications: | MS. SDS |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Purity: | > 95% by SDS - PAGE |
| Species: | Human |
| Formulation: | 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3 |
| Tag: | T7 |
| Amino Acid Sequence: | MDKDCEMKRT TLDSPLGKLE LSGCEQGLHE IKLLGKGTSA ADAVEVPAPA AVLGGPEPLM QCTAWLNAYF HQPEAIEEEP VPALHHPVFQ QESFTRQVLW KLLKVVKFGE VISYQQLAAL AGNPKAARAV GGAMRGNPVP ILIPCHRVVC SSGAVGNYSG GLAVKEWLLA HEGHRLGKPG LGGSSGLAGA WLKGAGATSG SPPAGRN |
| Expression System: | E. coli |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | MGMT O-6-methylguanine-DNA methyltransferase [Homo sapiens] |
| Gene ID NCBI: | 4255 |
| Synonyms: | MGMT; O-6-methylguanine-DNA methyltransferase; methylated-DNA-protein-cysteine methyltransferase; 6-O-methylguanine-DNA methyltransferase; methylguanine-DNA methyltransferase; O-6-methylguanine-DNA-alkyltransferase; EC2.1.1.63; O6-methylguanine-DNA methyltransferase |
| mRNA Refseq: | NM_002412 |
| Protein Refseq: | NP_002403 |
| MIM: | 156569 |
| UniProt ID: | P16455 |
| Chromosome Location: | 10q26 |
| Function: | DNA binding; DNA-methyltransferase activity; metal ion binding; methylated-DNA-[protein]-cystein S-methyltransferase activity; methyltransferase activity; transferase activity |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0142 | Recombinant Human MGMT Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0164 | Lomeguatrib | Inquiry |
| ◆ Antibodies | ||
| EAb-0230 | O6-Methylguanine-DNA methyltransferase Polyclonal Antibody | Inquiry |
| EAb-0351 | MGMT Polyclonal Antibody | Inquiry |
| ◆ Cell Lines | ||
| CL-0394 | Human MGMT Knockout Cell Line 2bp deletion | Inquiry |
| Related Gene / Proteins | |||
| MGMT | |||
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