| Cat.No.: | PE-1088 |
| Product Name: | Recombinant Human KMT2A Complex, His-tagged |
| Product Overview: | Recombinant Human MLL1(3745-3969), WDR5(22-334), RbBP5(1-538), Ash2L(2-534), DPY-30(1-99) protein, fused with N-terminal His-tag on all subunits, was expressed in E.coli. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 212.0 kDa |
| Purity: | >90% by SDS-PAGE |
| Species: | Human |
| Formulation: | 20 mM Tris-HCl, pH 7.5, 300 mM NaCl, 1 mM TCEP (tris(2-carboxyethyl)phosphine HCl), 10% (w/v) glycerol, 1 µM ZnCl2. |
| Tag: | His |
| Expression System: | E. coli |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | KMT2A lysine (K)-specific methyltransferase 2A [ Homo sapiens ] |
| Gene ID NCBI: | 4297 |
| Official Symbol: | KMT2A |
| Synonyms: | HRX; MLL; MLL1; TRX1; ALL-1; CXXC7; HTRX1; MLL1A; WDSTS; MLL-AF9; MLL/GAS7; TET1-MLL; CDK6/MLL fusion protein; CXXC-type zinc finger protein 7; MLL-AF4 der(11) fusion protein; MLL/ENL fusion protein; MLL/GAS7 fusion protein; MLL/GMPS fusion protein; MLL/hCDCrel fusion protein; lysine N-methyltransferase 2A; mixed lineage leukemia 1; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); rearranged MLL protein; trithorax-like protein; zinc finger protein HRX |
| mRNA Refseq: | NM_001197104 |
| Protein Refseq: | NP_001184033 |
| MIM: | 159555 |
| UniProt ID: | Q03164 |
| Chromosome Location: | 11q23 |
| Function: | AT DNA binding; chromatin binding; core promoter sequence-specific DNA binding |
| Product Types | ||
| ◆ Synthetic Peptides | ||
| SP-0172 | Human KMT2C / MLL3 peptide | Inquiry |
| ◆ Cell Lines | ||
| CL-0216 | Human KMT2A Knockout Cell Line 32bp deletion | Inquiry |
| CL-0475 | Human KMT2A Knockout Cell Line 32bp deletion | Inquiry |
| ◆ Research Kits | ||
| EKIT-0477 | SMYD2 (KMT3C) Chemiluminescent Assay Kit | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-1085 | Recombinant Human KMT2A, GST-tagged | Inquiry |
| Related Gene / Proteins | |||
| KMT1B | KMT1E | KMT2A | KMT2B |
| KMT2C | KMT2D | KMT2E | KMT3A |
| KMT3B | KMT3C | KMT5A | KMT6 |
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