| Cat.No.: | PE-1054 |
| Product Name: | Recombinant Human PRMT1, His-tagged |
| Product Overview: | Recombinant human PRMT1 produced in SF21 cells is fused to a His-tag. |
| Description: | Protein arginine N-methyltransferase 1(PRMT1) is a type I methyltransferase that transfers a methyl group from S-adenosylmethionine to guanidino nitrogens of arginine residues to form monomethylarginine and asymmetric dimethylarginine. Functions of type I arginine methylation in proteins may include regulation of transcription, modulation of the affinity of nucleic acid-binding proteins, regulation of interferon signaling pathways, and targeting of nuclear proteins. |
| Applications: | Study of enzyme kinetics and regulation, dephosphorylation of target substrates, and inhibitor screening. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Purity: | ≥90% (SDS-PAGE). |
| Species: | Human |
| Formulation: | Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 0.2% NP-40, 50mM imidazole and 10% glycerol. |
| Tag: | His |
| Activity: | 50-100ng are required for standard HAT assay. |
| Expression System: | Sf21 Insect Cells |
| Concentrations: | 0.5mg/ml. |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | PRMT1 protein arginine methyltransferase 1 [ Homo sapiens ] |
| Gene ID NCBI: | 3276 |
| Synonyms: | HMT1 hnRNP methyltransferase-like 2 isoform 3; protein arginine methyltransferase 1; ANM1; HCP1; IR1B4; HRMT1L2; PRMT1; HMT1 hnRNP methyltransferase-like 2; interferon receptor 1-bound protein 4; protein arginine N-methyltransferase 1; HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 2; EC 2.1.1.; HMT1 hnRNP methyltransferase-like 2 (S. cerevisiae); protein arginine methyltransferase 1 |
| mRNA Refseq: | NM_198318 |
| Protein Refseq: | NP_938074 |
| MIM: | 602950 |
| UniProt ID: | Q8WUW5 |
| Chromosome Location: | 19q13.3 |
| Function: | N-methyltransferase activity; protein binding; transferase activity |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
| BSM-0047 | SGC707 | Inquiry |
| ◆ Antibodies | ||
| EAb-0048 | PRMT6 Polyclonal Antibody | Inquiry |
| EAb-0049 | PRMT7 Polyclonal Antibody | Inquiry |
| EAb-0050 | PRMT1 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| Pr-SET7 | PRC1 | PRC2 | PRDM1 |
| PRDM10 | PRDM11 | PRDM12 | PRDM13 |
| PRDM14 | PRDM15 | PRDM16 | PRDM17 |
| PRDM2 | PRDM3 | PRDM4 | PRDM5 |
| PRDM6 | PRDM7 | PRDM8 | PRDM9 More > |
| PREP1 | PRIM2 | PRKAA2 | PRKCA |
| PRKCB | PRKCE | PRKDC | PRKRIP1 |
| PRMT | prmt1 | PRMT2 | PRMT3 |
| PRMT5 | prmt6 | PRMT7 | PRMT8 |
| PRMT9 | Progerin | Protamine 2 | Prox1 |
| PRPF31 | PRPF40A | PRSS12 | PRSS55 |
| PRTFDC1 | |||
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