| Cat.No.: | PE-1051 |
| Product Name: | Recombinant Mouse Carm1 Protein, FLAG-tagged |
| Product Overview: | Recombinant Mouse Carm1 fused with FLAG tag at N-terminal was expressed in Insect cells. |
| Description: | Carm1 / Prmt4 (Coactivator-associated arginine methyltransferase 1 or Carm1) is a protein arginine N-methyltransferase that catalyzes the mono- and asymmetric dimethylation of arginine residues in its substrate proteins. It serves as a coactivator of transcription and also plays a role in nuclear receptors. Carm1 methylates histone H3 at Arg2, Arg17 and Arg26; it also methylates a number of non-histone substrates involved in the regulation and mechanism of gene expression. |
| Applications: | Recombinant Carm1 / Prmt4 is suitable for use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | ~67 kDa |
| Species: | Mouse |
| Formulation: | In 25 mM HEPES (pH 7.5), 300 mM NaCl, 5% glycerol and 0.2 mg/ml 3X FLAG peptide. |
| Tag: | FLAG |
| Activity: | Specifically mediates the methylation of H3R17. |
| Expression System: | Insect Cells |
| Concentrations: | 0.6 µg/µl |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | Carm1 coactivator-associated arginine methyltransferase 1 [ Mus musculus ] |
| Gene ID NCBI: | 59035 |
| Official Symbol: | Carm1 |
| Synonyms: | CARM1; coactivator-associated arginine methyltransferase 1; histone-arginine methyltransferase CARM1; protein arginine methyltransferase; protein arginine N-methyltransferase 4; Prmt4; MGC46828; |
| mRNA Refseq: | NM_021531 |
| Protein Refseq: | NP_067506 |
| UniProt ID: | Q9WVG6 |
| Product Types | ||
| ◆ Synthetic Peptides | ||
| SP-0008 | PRMT4 peptide substrate, Biotin-labeled | Inquiry |
| ◆ Cell Lines | ||
| CL-0050 | Human CARM1 Knockout Cell Line 8bp deletion | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0123 | Ellagic acid | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0134 | Recombinant Human CARM1 293 Cell Lysate | Inquiry |
| EL-0148 | Recombinant Human CAMTA2 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| CABIN1 | CAF1 | CAMKIV | CAMTA2 |
| CAPNS2 | CARHSP1 | CARM1 | CASC3 |
| CASP | CASP1 | CASP3 | |
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