| Cat.No.: | PE-1000 |
| Product Overview: | Recombinant Human SET8 (amino acids 195-352) was expressed in an E.coli expression system with N-terminal GST tag. MW = 44 kDa. |
| Description: | Histone-lysine N-methyltransferase SETD8 is an enzyme that in humans is encoded by the SETD8 gene. |
| Applications: | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Purity: | > 70%. |
| Species: | Human |
| Formulation: | 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 20% glycerol, and 3 mM DTT. |
| Tag: | GST |
| Expression System: | E. coli |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | SETD8 SET domain containing (lysine methyltransferase) 8 [ Homo sapiens ] |
| Gene ID NCBI: | 387893 |
| Synonyms: | SET domain containing (lysine methyltransferase) 8; SET8; KMT5A; SET07; PR-Set7; SETD8; SET domain-containing 8; PR/SET domain containing protein 8; H4-K20-specific histone methyltransferase; EC 2.1.1.43; PR/SET07; PRSET7; H4-K20-HMTase SETD8; Lysine N-methyltransferase 5A; PR/SET domain-containing protein 07; SET domain-containing protein 8 |
| mRNA Refseq: | NM_020382 |
| Protein Refseq: | NP_065115 |
| MIM: | 607240 |
| UniProt ID: | Q9NQR1 |
| Chromosome Location: | 12q24.31 |
| Function: | histone-lysine N-methyltransferase activity; methyltransferase activity; protein binding; transcription corepressor activity; transferase activity |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
| ◆ Antibodies | ||
| EAb-0030 | SETD8 Polyclonal Antibody | Inquiry |
| EAb-0031 | SETDB1 Polyclonal Antibody | Inquiry |
| EAb-0032 | Setd1a Polyclonal Antibody | Inquiry |
| EAb-0033 | Setd1b Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| SENP3 | SENP8 | SET | SET1 |
| SET2 | SET7 | SET8 | SET9 |
| SETBP1 | SETD1A | SETD1B | SETD2 |
| SETD3 | SETD5 | SETD6 | SETD7 |
| SETD8 | SETD9 | SetDB1 | SETDB2 More > |
| SETMAR | |||
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