| Cat.No.: | PE-0998 |
| Product Name: | Recombinant Human EHMT1 Protein, GST-tagged |
| Product Overview: | Recombinant Human EHMT1 protein, fused with N-terminal GST-tag, was expressed in E. coli. |
| Description: | GLP, in complex with the highly homologous G9a, is the major histone H3 lysine-9 (H3K9) methyltransferase for euchromatin and can also dimethylate p53K373, a modification correlating with levels of inactive p53. This latter result, along with the fact tha |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 80.0 kDa |
| Purity: | >80% by SDS-PAGE |
| Species: | Human |
| Formulation: | 25.4 mM Na2HPO4/NaH2PO4, pH 7.4, 137 mM NaCl, 2.7 mM KCl, 3 mM DTT, 30% (w/v) glycerol. |
| Tag: | GST |
| Expression System: | E. coli |
| Protein Length: | 894-1298 |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | EHMT1 euchromatic histone-lysine N-methyltransferase 1 [ Homo sapiens ] |
| Gene ID NCBI: | 79813 |
| Official Symbol: | EHMT1 |
| Synonyms: | EHMT1; euchromatic histone-lysine N-methyltransferase 1; euchromatic histone methyltransferase 1; histone-lysine N-methyltransferase EHMT1; bA188C12.1; Eu HMTase1; FLJ12879; KIAA1876; KMT1D; H3-K9-HMTase 5; G9a like protein; G9a-like protein 1; lysine N-methyltransferase 1D; histone H3-K9 methyltransferase 5; histone-lysine N-methyltransferase, H3 lysine-9 specific 5; GLP; GLP1; FP13812; EUHMTASE1; Eu-HMTase1; RP11-188C12.1; DKFZp667M072; |
| mRNA Refseq: | NM_001145527 |
| Protein Refseq: | NP_001138999 |
| MIM: | 607001 |
| UniProt ID: | Q9H9B1 |
| Chromosome Location: | 9 |
| Function: | histone methyltransferase activity (H3-K27 specific); histone methyltransferase activity (H3-K9 specific); histone-lysine N-methyltransferase activity; metal ion binding; methyltransferase activity; p53 binding; protein binding; protein-lysine N-methyltra |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0025 | BIX01294 (hydrochloride hydrate) | Inquiry |
| BSM-0026 | UNC0224 | Inquiry |
| BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
| ◆ Cell Lines | ||
| CL-0059 | Human EHMT1 Knockout Cell Line 7bp deletion | Inquiry |
| CL-0060 | Human EHMT2 Knockout Cell Line 34bp deletion | Inquiry |
| Related Gene / Proteins | |||
| EHD2 | EHMT1 | EHMT2 | |
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