| Cat.No.: | PE-0966 |
| Product Name: | Recombinant Human BRCA2, His & GST-tagged |
| Product Overview: | A DNA sequence encoding the human BCCIP (AAH09771.1) (Met1-Val314) was expressed with the N-terminal polyhistidine-tagged GST tag at the N-terminus. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | The recombinant human BCCIP/GST chimera consists of 551 amino acids and has a calculated molecular mass of 64 kDa. The recombinant protein migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions. |
| Purity: | >85 % as determined by SDS-PAGE |
| Species: | Human |
| Formulation: | Lyophilized from sterile PBS, pH7.4. |
| Tag: | His & GST |
| Endotoxin: | < 1.0 eu per μg of the protein as determined by the LAL method. |
| Reconstitution: | Hardcopy of COA with reconstitution instruction is sent along with the products. |
| Expression System: | Baculovirus-Insect Cells |
| Protein Length: | Met1-Val314 |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | BRCA2 breast cancer 2, early onset [ Homo sapiens ] |
| Gene ID NCBI: | 675 |
| Synonyms: | BRCA2; breast cancer 2, early onset; FACD, FANCD, FANCD1, Fanconi anemia, complementation group D1; breast cancer type 2 susceptibility protein; BRCA1/BRCA2 containing complex; subunit 2; BRCC2; FAD; FAD1; fanconi anemia group D1 protein; breast cancer 2 tumor suppressor; BRCA1/BRCA2-containing complex, subunit 2; breast cancer susceptibility protein BRCA2; breast and ovarian cancer susceptibility gene, early onset; FACD; GLM3; FANCB; FANCD; PNCA2; FANCD1; BROVCA2; |
| mRNA Refseq: | NM_000059 |
| Protein Refseq: | NP_000050 |
| MIM: | 600185 |
| UniProt ID: | P51587 |
| Chromosome Location: | 13q12-q13 |
| Function: | DNA binding; H3 histone acetyltransferase activity; H4 histone acetyltransferase activity; gamma-tubulin binding; NOT histone acetyltransferase activity; protease binding; protein binding; single-stranded DNA binding; |
| Product Types | ||
| ◆ Synthetic Peptides | ||
| SP-0001 | Bromodomain Non-Acetylated Ligand 4 | Inquiry |
| SP-0002 | Bromodomain Non-Acetylated Ligand 3 | Inquiry |
| SP-0003 | Bromodomain Non-Acetylated Ligand 1 | Inquiry |
| SP-0004 | Bromodomain Ligand 3 | Inquiry |
| SP-0006 | Bromodomain Ligand 4 | Inquiry |
| Related Gene / Proteins | |||
| BRCA1 | BRCA2 | BRCC3 | BRD |
| brd1 | brd2 | brd3 | brd4 |
| BRD7 | BRD8 | brd9 | brdt |
| BRL | BRM | BRMS1 | BRPF1 |
| BRPF2 | brpf3 | BRWD1 | BRWD3 |
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