| Cat.No.: | PE-0750 |
| Product Overview: | Recombinant Mouse Runx2 aa. (Ser125~Ala352 (Accession # Q08775)) fused with N-terminal His tag was produced in E. coli cells. |
| Description: | This gene encodes a member of the runt domain-containing family of transcription factors. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. |
| Applications: | SDS-PAGE; WB; ELISA; IP. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Freeze-dried powder |
| Molecular Weight: | Predicted Molecular Mass: 26.5kDa |
| Purity: | >95% |
| Species: | Mouse |
| Tag: | His |
| Endotoxin: | <1.0EU per 1µg (determined by the LAL method) |
| Reconstitution: | Reconstitute in sterile PBS, pH7.2-pH7.4. |
| Expression System: | E. coli |
| Isoelectric Point: | The isoelectric point is 9.7. |
| Protein Length: | Ser125~Ala352 (Accession # Q08775) |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | Runx2 runt related transcription factor 2 [ Mus musculus (house mouse) ] |
| Gene ID NCBI: | 12393 |
| Official Symbol: | Runx2 |
| Synonyms: | Runx2; runt related transcription factor 2; Cbf; LS3; AML3; Osf2; Cbfa1; Cbfa-1; PEBP2aA; Pebp2a1; Pebpa2a; runt-related transcription factor 2; AKV core binding factor; CBF-alpha-1; PEA2-alpha A; PEBP2 alpha A; SL3-3 enhancer factor 1 alpha A subunit; acute myeloid leukemia 3 protein; core binding factor alpha 1; osteoblast-specific transcription factor 2; polyomavirus enhancer-binding protein 2 alpha A subunit; runt domain, alpha subunit 1 |
| mRNA Refseq: | NM_001146038.2 |
| Protein Refseq: | NP_001139510.1 |
| UniProt ID: | Q08775 |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0042 | Runx1/AML1-ETO Polyclonal Antibody | Inquiry |
| EAb-0313 | RUNX2 Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0092 | Recombinant Human RUNX2 293 Cell Lysate | Inquiry |
| EL-0093 | Recombinant Human RUNX2 293 Cell Lysate | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0746 | Recombinant Human RUNX2 | Inquiry |
| Related Gene / Proteins | |||
| Runx1 | RUNX2 | RUVB2 | RUVBL1 |
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