| Cat.No.: | PE-0694 |
| Product Name: | Recombinant Human SP1 protein, His & GST-tagged |
| Product Overview: | Recombinant Human SP1 aa. (Leu260~Ala591) fused with N-terminal His & GST tag was produced in E. coli cells. |
| Description: | The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. |
| Applications: | Positive Control; Immunogen; SDS-PAGE; WB. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Freeze-dried powder |
| Molecular Weight: | 63kDa as determined by SDS-PAGE reducing conditions. |
| Purity: | >92% |
| Species: | Human |
| Tag: | His & GST |
| Endotoxin: | <1.0EU per 1ug (determined by the LAL method) |
| Reconstitution: | Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
| Expression System: | E. coli |
| Isoelectric Point: | The isoelectric point is 5.6. |
| Protein Length: | Leu260~Ala591 |
| Concentrations: | 200μg/mL |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | SP1 Sp1 transcription factor [ Homo sapiens (human) ] |
| Gene ID NCBI: | 6667 |
| Official Symbol: | SP1 |
| Synonyms: | SP1; Sp1 transcription factor; transcription factor Sp1; specificity protein 1 |
| mRNA Refseq: | NM_001251825.1 |
| Protein Refseq: | NP_001238754.1 |
| UniProt ID: | P08047 |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0089 | Recombinant Human SP2 Cell Lysate | Inquiry |
| ◆ Cell Lines | ||
| CL-0161 | Human SP1 Knockout Cell Line 2bp deletion | Inquiry |
| CL-0169 | Human SP140L Knockout Cell Line | Inquiry |
| CL-0170 | Human SP100 Knockout Cell Line 20bp deletion | Inquiry |
| CL-0171 | Human SP110 Knockout Cell Line 7bp deletion | Inquiry |
| Related Gene / Proteins | |||
| SP1 | SP100 | SP110 | SP140 |
| SP140L | SP2 | SP3 | SP6 |
| SPDL1 | SPF30 | SPIN1 | SPOP |
| SPT16 | SPT3 | Spt6 | SPTY2D1 |
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