| Cat.No.: | PE-0684 |
| Product Name: | Recombinant Human Sp1 Transcription Factor |
| Product Overview: | Recombinant human SP1 protein was expressed in Sf9 insect cells . |
| Description: | SP1 belongs to the family of zinc finger DNA binding proteins in mammalian cells. This protein mediates transcriptional activity through specific DNA sequences that are found in a number of viral and cellular gene promoters. SP1 has been shown to associate with other mammalian gene coactivator proteins to regulate gene transcription. |
| Applications: | Useful for the stimulation of LSD1 enzyme activity. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Species: | Human |
| Formulation: | 15 ug of recombinant SP1 protein in 5uM ZnSO4, 50 mM KCl, 2mM DTT, 12 mM HEPES-KOH (pH 7.5), 6 mM MgCl2, 0.1% NP40 and 50% glycerol. |
| Expression System: | Sf9 Insect Cells |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | SP1 Sp1 transcription factor [ Homo sapiens ] |
| Gene ID NCBI: | 6667 |
| Synonyms: | SP1; Sp1 transcription factor; Sp1 transcription factor; specificity protein 1; TSFP1; Transcription factor Sp1 |
| mRNA Refseq: | NM_003109 |
| Protein Refseq: | NP_003100 |
| MIM: | 189906 |
| UniProt ID: | P08047 |
| Chromosome Location: | 12q13.1 |
| Function: | DNA binding; RNA polymerase II transcription factor activity; double-stranded DNA binding; histone deacetylase binding; metal ion binding; promoter binding; protein C-terminus binding; protein homodimerization activity; transcription activator activity; transcription factor activity; zinc ion binding |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0089 | Recombinant Human SP2 Cell Lysate | Inquiry |
| ◆ Cell Lines | ||
| CL-0161 | Human SP1 Knockout Cell Line 2bp deletion | Inquiry |
| CL-0169 | Human SP140L Knockout Cell Line | Inquiry |
| CL-0170 | Human SP100 Knockout Cell Line 20bp deletion | Inquiry |
| CL-0171 | Human SP110 Knockout Cell Line 7bp deletion | Inquiry |
| Related Gene / Proteins | |||
| SP1 | SP100 | SP110 | SP140 |
| SP140L | SP2 | SP3 | SP6 |
| SPDL1 | SPF30 | SPIN1 | SPOP |
| SPT16 | SPT3 | Spt6 | SPTY2D1 |
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