| Cat.No.: | PE-0212 |
| Product Overview: | Recombinant Human EZH1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
| Description: | EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008 [PubMed 19026780]). |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Species: | Human |
| Tag: | His |
| Expression System: | E. coli |
| Protein Length: | 161-267a.a. |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | EZH1 enhancer of zeste homolog 1 (Drosophila) [ Homo sapiens ] |
| Gene ID NCBI: | 2145 |
| Synonyms: | EZH1; enhancer of zeste homolog 1 (Drosophila); enhancer of zeste (Drosophila) homolog 1; histone-lysine N-methyltransferase EZH1; KIAA0388; KMT6B; ENX-2; |
| mRNA Refseq: | NM_001991 |
| Protein Refseq: | NP_001982 |
| MIM: | 601674 |
| UniProt ID: | Q92800 |
| Chromosome Location: | 17q21.1-q21.3 |
| Function: | DNA binding; chromatin binding; histone methyltransferase activity (H3-K27 specific); methyltransferase activity; transferase activity; |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0006 | GSK343 | Inquiry |
| BSM-0059 | 3-Deazaneplanocin A | Inquiry |
| BSM-0060 | 3-Deazaneplanocin A hydrochloride | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0024 | Recombinant Human EZH1 293 Cell Lysate | Inquiry |
| EL-0025 | Recombinant Human EZH2 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| ezh1 | EZH2 | ||
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