| Cat.No.: | PE-0135 |
| Product Name: | Recombinant Human SIRT1 Protein, His-tagged |
| Product Overview: | Recombinant Human SIRT1 protein, fused with N-terminal His-tag, was expressed in E. coli. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 83.2 kDa |
| Purity: | >85% by SDS-PAGE |
| Species: | Human |
| Formulation: | 50 mM Tris/HCl pH 7.5, 100 mM NaCl, 10% glycerol (v/v) |
| Tag: | His |
| Expression System: | E. coli |
| Protein Length: | 1-747 |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | SIRT1 sirtuin 1 [ Homo sapiens ] |
| Gene ID NCBI: | 23411 |
| Official Symbol: | SIRT1 |
| Synonyms: | SIRT1; sirtuin 1; sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae) , sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 1; NAD-dependent deacetylase sirtuin-1; SIR2L1; hSIR2; hSIRT1; SIR2alpha; si |
| mRNA Refseq: | NM_001142498 |
| Protein Refseq: | NP_001135970 |
| MIM: | 604479 |
| UniProt ID: | Q96EB6 |
| Chromosome Location: | 10q21 |
| Function: | HLH domain binding; NOT NAD+ ADP-ribosyltransferase activity; NAD+ binding; NAD-dependent histone deacetylase activity; NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent protein deacetylase activity; NAD-dependent protein deacetyl |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0016 | Recombinant Human SIRT1 Lysate | Inquiry |
| EL-0017 | Recombinant Human SIRT2 293 Cell Lysate | Inquiry |
| EL-0018 | Recombinant Human SIRT3 293 Cell Lysate | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0017 | Fluorogenic Sirtuin 5 Substrate | Inquiry |
| SP-0018 | Fluorogenic Sirtuin 6 Substrate | Inquiry |
| Related Gene / Proteins | |||
| Siah2 | SIK1 | SIMC1 | SIN3A |
| SIN3B | SIP1 | Sir2p | SIRT |
| SIRT1 | SIRT2 | SIRT3 | SIRT4 |
| SIRT5 | sirt6 | SIRT7 | SIX3 |
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