| Cat.No.: | PE-0068 |
| Product Name: | Recombinant Mouse HDAC5 (Active), GST-tagged |
| Product Overview: | Recombinant mouse HDAC5 (617-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
| Description: | HDAC5 or Histone deacetylase 5 belongs to the class II histone deacetylase/acuc/apha family that possesses histone deacetylase activity and represses transcription when tethered to a promoter. HDAC 5 plays a critical role in transcriptional regulation, cell cycle progression, and developmental events and also acts as a potential therapeutic target for the prevention of atherosclerosis. HDAC5 can co-immunoprecipitates with HDAC3 family members forming multicomplex proteins. HDAC5 can also interact with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. HDAC5 gene is thought to be associated with colon cancer. |
| Applications: | HDAC Assay, Western Blot |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | ~80 kDa |
| Purity: | >90% |
| Species: | Mouse |
| Formulation: | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Tag: | GST |
| Activity: | 110 RLU/min/ng |
| Expression System: | Sf9 Insect Cells |
| Protein Length: | 617 aa-end |
| Concentrations: | 0.1μg/μl |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | Hdac5 histone deacetylase 5 [ Mus musculus ] |
| Gene ID NCBI: | 15184 |
| Synonyms: | HDAC5; histone deacetylase 5; HD5; histone deacetylase 4; histone deacetylase mHDA1; Hdac4; mHDA1; AI426555; mKIAA0600; |
| mRNA Refseq: | NM_001077696 |
| Protein Refseq: | NP_001071164 |
| Function: | histone deacetylase activity; hydrolase activity; protein binding; protein kinase C binding; repressing transcription factor binding; transcription corepressor activity; transcription corepressor activity; transcription factor binding; |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
| EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
| EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
| EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0007 | Tubacin | Inquiry |
| Related Gene / Proteins | |||
| HDAC | HDAC1 | HDAC10 | HDAC11 |
| HDAC2 | HDAC3 | hdac4 | hdac5 |
| HDAC6 | hdac7 | HDAC8 | hdac9 |
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