| Cat.No.: | PE-0030 |
| Product Name: | Recombinant Human HDAC2 |
| Product Overview: | Recombinant full length Human HDAC2 with a C-terminal proprietary tag. Expressed by baculovirus in Sf9 insect cells. Genbank Number: |
| Description: | This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. |
| Tissue Specificity: | Widely expressed; lower levels in brain and lung. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Molecular Weight: | 92.000kDa inclusive of tags |
| Species: | Human |
| Sequence Similarities: | Belongs to the histone deacetylase family. HD type 1 subfamily. |
| Expression System: | Baculovirus |
| Protein Length: | 488 amino acids |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | HDAC2 histone deacetylase 2 [ Homo sapiens ] |
| Gene ID NCBI: | 3066 |
| Official Symbol: | HDAC2 |
| Synonyms: | HDAC2; histone deacetylase 2; RPD3; YAF1; |
| mRNA Refseq: | NM_001527 |
| Protein Refseq: | NP_001518 |
| MIM: | 605164 |
| UniProt ID: | Q92769 |
| Chromosome Location: | 6q21 |
| Function: | NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); chromatin binding; enzyme binding; |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
| EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
| EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
| EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0007 | Tubacin | Inquiry |
| Related Gene / Proteins | |||
| HDAC | HDAC1 | HDAC10 | HDAC11 |
| HDAC2 | HDAC3 | hdac4 | hdac5 |
| HDAC6 | hdac7 | HDAC8 | hdac9 |
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