| Cat.No.: | PE-0028 |
| Product Name: | Recombinant Human Histone Deacetylase 2, His-tagged |
| Product Overview: | Recombinant human HDAC2 protein was expressed with c-terminal His-tag in high-5 cells using baculovirus expression system and purified by using conventional chromatography techniques. |
| Description: | HDAC2 belongs to the histone deacetylase family that act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues on the N-terminal region of the core histones. It forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. It also plays an important role in transcriptional regulation, cell cycle progression and developmental events. |
| Applications: | SDS-PAGE |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 56.4 kDa (496aa) |
| Purity: | > 85% by SDS - PAGE |
| Species: | Human |
| Formulation: | Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 20% glycerol, 0.1M NaCl, 1mM DTT and 0.1mM PMSF. |
| Tag: | His |
| Amino Acid Sequence: | MAYSQGGGKK KVCYYYDGDI GNYYYGQGHP MKPHRIRMTH NLLLNYGLYR KMEIYRPHKA TAEEMTKYHS DEYIKFLRSI RPDNMSEYSK QMQRFNVGED CPVFDGLFEF CQLSTGGSVA GAVKLNRQQT DMAVNWAGGL HHAKKSEASG FCYVNDIVLA ILELLKYHQR VLYIDIDIHH GDGVEEAFYT TDRVMTVSFH KYGEYFPGTG DLRDI |
| Expression System: | Hi-5 Cells |
| Protein Length: | 1-488 |
| Concentrations: | 0.25 mg/ml |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | HDAC2 histone deacetylase 2 [ Homo sapiens ] |
| Gene ID NCBI: | 3066 |
| Synonyms: | HDAC2; RPD3; YAF1; histone deacetylase 2; OTTHUMP00000040427; YY1-associated factor 1; transcriptional regulator homolog RPD3; EC 3.5.1.98; HD2 |
| mRNA Refseq: | NM_001527 |
| Protein Refseq: | NP_001518 |
| MIM: | 605164 |
| Chromosome Location: | 6q21 |
| Function: | enzyme binding; histone deacetylase activity; hydrolase activity; specific transcriptional repressor activity; transcription activator activity; transcription factor activity; transcription factor binding |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
| EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
| EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
| EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0007 | Tubacin | Inquiry |
| Related Gene / Proteins | |||
| HDAC | HDAC1 | HDAC10 | HDAC11 |
| HDAC2 | HDAC3 | hdac4 | hdac5 |
| HDAC6 | hdac7 | HDAC8 | hdac9 |
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