5-Methylcytosine (5-mC) Monoclonal Antibody (5MC-CD)

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Cat.No.:  EAb-3210
Product Overview:  Mouse monoclonal (5MC-CD) to detect 5-methylcytosine (5-mC) (FITC)
Antibody Type:  Monoclonal
Clone Designation:  5MC-CD
Immunogen:  Chemical/ Small Molecule corresponding to 5-methylcytosine (5-mC) conjugated to Bovine Serum Albumin (BSA).
Host:  Mouse
Isotype:  IgM
Purification:  Purified IgM
Appearance:  Liquid
Formulation:  50% Glycerol, 50% PBS
Applications:  Southern Blot, ICC/IF
Species Reactivity:  a wide range of other species
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  5-methylcytosine, 5-methyl cytosine
Scientific Background:  5-Methylcytosine (5-Methylcytidine) is a modified base that is found in the DNA of plants and vertebrates. DNA methylation is an epigenetic event in which DNA methyltransferases (DNMTs) catalyze the reaction of a methyl group to the fifth carbon of cytosine in a CpG dinucleotide. This modification helps to control gene expression and is also involved in genomic imprinting, while aberrant DNA methylation is often associated with disease.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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