| Cat.No.: | EAb-2846 |
| Product Name: | KDM5B/PLU1/Jarid1B Polyclonal Antibody |
| Product Overview: | Rabbit polyclonal to detect KDM5B/PLU1/Jarid1B |
| Antibody Type: | Polyclonal |
| Immunogen: | Synthetic peptide corresponding to Human KDM5B/ PLU1/ Jarid1B aa 1534-1544 (C terminal). |
| Immunogen Sequence: | RCTVKDAPSRK |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Immunogen affinity purified |
| Appearance: | Liquid |
| Formulation: | pH: 7.4; 0.02% Sodium azide, 0.1% BSA, 50% Glycerol, 49% Tris buffered saline |
| Applications: | ICC/IF, Flow Cyt |
| Species Reactivity: | Human |
| Storage: | -20°C. |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q9UGL1; NP_006609.3 |
| Alternative Name: | Cancer/testis antigen 31 antibody/CT31 antibody/Histone demethylase JARID1B antibody |
| Scientific Background: | Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0002 | AT9283 | Inquiry |
| ◆ Cell Lines | ||
| CL-0015 | Human KDM5B Knockout Cell Line 14bp deletion | Inquiry |
| CL-0017 | Human JARID2 Knockout Cell Line 11bp deletion | Inquiry |
| ◆ Antibodies | ||
| EAb-0071 | KDM1B Polyclonal Antibody | Inquiry |
| EAb-0079 | JARID2 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| JADE1 | JAK | JAK1 | JAK2 |
| JAK3 | JAKMIP1 | JARID | JARID1 |
| JARID1A | JARID1B | JARID1C | JARID2 |
| KDM1 | KDM1A | KDM1B | KDM2 |
| KDM2A | KDM2B | KDM3A | KDM3B More > |
| KDM4 | KDM4A | KDM4B | KDM4C |
| KDM4D | KDM4E | KDM5 | KDM5A |
| KDM5B | KDM5C | KDM5D | KDM6A |
| KDM6B | KDM6C | KDM7 | KDM7A |
| KDM7B | KDM8 | PLC | PLU1 |
| PLZF | |||
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