ING2 Polyclonal Antibody

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Cat.No.:  EAb-2768
Product Overview:  Goat polyclonal to detect ING2
Antibody Type:  Polyclonal
Immunogen:  Synthetic peptide corresponding to C terminal amino acids 267-280 of Human ING2.
Immunogen Sequence:  DKSTEKTKKDRRSR
Host:  Goat
Isotype:  IgG
Purification:  Immunogen affinity purified
Appearance:  Liquid
Formulation:  pH: 7.30; 0.02% Sodium azide, 0.05% Tris, 0.5% BSA
Applications:  WB, ICC/IF
Species Reactivity:  Human
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  ING 1 like tumor suppressor protein antibody/ING 1L antibody/ING 2 antibody
Scientific Background:  Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs).

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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