| Cat.No.: | EAb-2389 |
| Product Overview: | Anti-5-mC (MOUSE) Monoclonal Antibody |
| Antibody Type: | Monoclonal |
| Clone Designation: | 33D3 |
| Immunogen: | Clone 33D3 recognizes the modified base 5-methylcytidine found in plant and vertebrate DNA. |
| Host: | Mouse |
| Isotype: | IgG |
| Purification: | Protein A Chromatography |
| Appearance: | Liquid |
| Formulation: | Purified IgG in 10 mM phosphate, 0.15 M NaCl and 0.01% thimerosal. |
| Applications: | MeDIP: 1 µg per IP; IHC (FFPE): 1:1000; WB: 1:250 dilution; ELISA: 1:10,000 dilution; ICC/IF; DB^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Not Species Specific |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Alternative Name: | 5-methylcytosine, 5-methyl cytosine |
| Scientific Background: | 5-Methylcytosine (5-Methylcytidine) is a modified base that is found in the DNA of plants and vertebrates. DNA methylation is an epigenetic event in which DNA methyltransferases (DNMTs) catalyze the reaction of a methyl group to the fifth carbon of cytosine in a CpG dinucleotide. This modification helps to control gene expression and is also involved in genomic imprinting, while aberrant DNA methylation is often associated with disease. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0001 | 5-Hydroxymethylcytosine (5-hmC) Polyclonal Antibody | Inquiry |
| EAb-0209 | 5-Hydroxymethyluridine Polyclonal Antibody | Inquiry |
| EAb-0226 | 5-Hydroxymethylcytosine (5-hmC) Polyclonal Antibody | Inquiry |
| EAb-0254 | 5-Methylcytosine (5-mC) Monoclonal Antibody (RM231) | Inquiry |
| EAb-0255 | 5-Hydroxymethylcytosine (5-hmC) Monoclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| 5-caC | 5-fC | 5-hmC | 5-Hydroxymethyluridine |
| 5-mC | 5-mCpA | ||
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