| Cat.No.: | EAb-2155 |
| Antibody Type: | Monoclonal |
| Immunogen: | This antibody was raised against a recombinant protein corresponding to amino acids 67 - 279 of human ING1. |
| Host: | Mouse |
| Isotype: | IgG2a |
| Molecular Weight: | 47 kDa |
| Purification: | Protein A Chromatography |
| Appearance: | Liquid |
| Formulation: | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. |
| Applications: | ICC/IF; WB |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | ING1 (Inhibitor Of Growth Family, Member 1) is a member of the inhibitor of growth (ING) family of proteins that play key roles in cell cycle arrest, apoptosis, cell aging, and the DNA damage response. ING1 contains a PHD domain that interacts with Histone H3K4me3. ING1 cooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. Implicated as a tumor suppressor. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0182 | Recombinant Human ING5 293 Cell Lysate | Inquiry |
| EL-0189 | Recombinant Human ING3 293 Cell Lysate | Inquiry |
| EL-0196 | Recombinant Human ING4 293 Cell Lysate | Inquiry |
| ◆ Antibodies | ||
| EAb-0317 | ING4 Polyclonal Antibody | Inquiry |
| ◆ Cell Lines | ||
| CL-0403 | Human INSL6 Knockout Cell Line | Inquiry |
| Related Gene / Proteins | |||
| ING1 | ING2 | ING3 | ING4 |
| ING5 | INHAT-1 | INHAT-2 | Ini1 |
| INSL6 | |||
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