| Cat.No.: | EAb-2077 |
| Product Name: | AP-2 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | This AP-2 antibody was raised against a synthetic peptide corresponding to amino acid residues 120-134 of human AP-2. |
| Host: | Rabbit |
| Isotype: | IgG |
| Molecular Weight: | 50 and 40 kDa |
| Purification: | Affinity Purified |
| Appearance: | Liquid |
| Formulation: | PBS containing 0.2% gelatin, 0.01% thimersol and 0.1% sodium azide. |
| Applications: | WB: 1:500 - 1:1,000; ChIP; IHC (FFPE); EMSA^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | AP-2 (activator protein 2 or AP2) transcription factors activate transcription and regulate gene expression during embryogenesis. There are four different isoforms of AP-2 (AP-2α, AP-2β, AP-2γ and AP-2δ). The family members share a common structure in which the N-terminal region is involved with transcriptional activation and the C-terminal region is involved in DNA binding. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0374 | APOBEC3D Polyclonal Antibody | Inquiry |
| EAb-0375 | APOBEC2 Polyclonal Antibody | Inquiry |
| EAb-0393 | APOBEC3G Polyclonal Antibody | Inquiry |
| EAb-0403 | APOBEC3C Polyclonal Antibody | Inquiry |
| ◆ Cell Lines | ||
| CL-0388 | Human APTX Knockout Cell Line 11bp deletion | Inquiry |
| Related Gene / Proteins | |||
| AP-2 | Ape1 | APOBEC2 | APOBEC3A |
| APOBEC3B | APOBEC3C | APOBEC3D | APOBEC3F |
| APOBEC3G | APOBEC3H | APOBEC4 | APTX |
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