| Cat.No.: | EAb-2008 |
| Antibody Type: | Polyclonal |
| Immunogen: | This DR6 antibody was raised against a cytoplasmic domain corresponding to amino acid residues 371-655 of human DR6. |
| Host: | Rabbit |
| Isotype: | IgG |
| Molecular Weight: | 66 kDa |
| Purification: | Affinity Purified |
| Appearance: | Liquid |
| Formulation: | PBS containing 0.02% sodium azide. |
| Applications: | WB: 1 - 2 µg/ml dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | DR6 (also known as Tumor Necrosis Factor Receptor Superfamily, member 21, TNFRSF21) is a member of the TNF-receptor superfamily. This receptor interacts with TRADD to mediate signal transduction of TNF receptors. It may activate NFκB (NFκB p50 & NFκB p65) and MAPK8/JNK and induce apoptosis. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-2007 | DR4 Monoclonal Antibody | Inquiry |
| EAb-2008 | DR6 Polyclonal Antibody | Inquiry |
| EAb-2112 | Drosha Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| DR4 | DR6 | Drosha | |
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