| Cat.No.: | EAb-1975 |
| Product Name: | GLI1 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | This GLI1 antibody was raised against a peptide within the C-terminal region of human GLI1. |
| Host: | Rabbit |
| Isotype: | IgG |
| Molecular Weight: | 120 kDa |
| Purification: | Affinity Purified |
| Appearance: | Liquid |
| Formulation: | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. |
| Applications: | WB: 1:500 - 1:2,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | GLI1 (Glioma-associated oncogene 1) is a zinc finger transcription factor and oncogene. GLI1 is part of the hedgehog signaling pathway, but is also activated in response to TGF-β signaling as well. GLI1 activates transcription of a number of genes that promote cell cycle progression. GLI1 is overexpressed as a result of constitutive activation of hedgehog signaling, which plays a role in the initiation of cancer. GLI1 also promotes self-renewal of neural stem cells. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0192 | GLI1 Polyclonal Antibody | Inquiry |
| EAb-1974 | GLIS1 Monoclonal Antibody | Inquiry |
| EAb-1975 | GLI1 Polyclonal Antibody | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0408 | Thielavin B | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-2516 | Recombinant Human GLYR1 protein | Inquiry |
| Related Gene / Proteins | |||
| GLI1 | GLI4 | GLIS1 | GliS2 |
| Glucose-6-phosphatase | GLYR1 | ||
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