| Cat.No.: | EAb-1950 |
| Antibody Type: | Polyclonal |
| Immunogen: | This INHAT-1/TAF-1a/TAF-1b antibody was raised against a mixture of synthetic peptides corresponding to amino acid residues 66-81 and 135-151 of human INHAT-1/TAF-1a/TAF-1β. |
| Host: | Rabbit |
| Isotype: | IgG |
| Molecular Weight: | 37 kDa |
| Purification: | Affinity Purified |
| Appearance: | Liquid |
| Formulation: | PBS containing 0.02% sodium azide and 0.1 mg/ml BSA. |
| Applications: | WB: 1 - 2 µg/ml dilution; ICC^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse, Rat |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | INHAT (also designated TAF-1α, TAF-1β and Inhibitor of Histone Acetyltransferases complex) binds to histones and masks them from being substrates for histone acetyltransferases (HATs). Endogenous INHAT subunits, which include the Set/TAF-Ibeta oncoprotein, and pp32 associate with chromatin in vivo and can block coactivator-mediated transcription when transfected in cells. Single phosphorylations within the Histone H3 tail blocks binding of INHAT, as well as simultaneous acetylation of multiple lysine residues. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0182 | Recombinant Human ING5 293 Cell Lysate | Inquiry |
| EL-0189 | Recombinant Human ING3 293 Cell Lysate | Inquiry |
| EL-0196 | Recombinant Human ING4 293 Cell Lysate | Inquiry |
| ◆ Antibodies | ||
| EAb-0317 | ING4 Polyclonal Antibody | Inquiry |
| ◆ Cell Lines | ||
| CL-0403 | Human INSL6 Knockout Cell Line | Inquiry |
| Related Gene / Proteins | |||
| ING1 | ING2 | ING3 | ING4 |
| ING5 | INHAT-1 | INHAT-2 | Ini1 |
| INSL6 | |||
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