| Cat.No.: | EAb-1884 |
| Product Name: | Oct-4 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | This Oct-4 antibody was raised against a peptide derived from human Oct-4. |
| Host: | Rabbit |
| Isotype: | IgG |
| Molecular Weight: | 45 kDa |
| Purification: | Affinity Purified |
| Appearance: | Liquid |
| Formulation: | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. |
| Applications: | ChIP: 10 µl per ChIP; ChIP-Seq: 10 µl each; ICC/IF: 1:200 dilution; WB: 1:1,000 - 1:5,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | Oct-4 (Octamer binding protein-4, POU5F1) is a member of the POU family of transcriptional activators. Oct-4 is critical for early embryogenesis and required for embryonic stem cell pluripotency. Oct-4 is expressed at high levels in undifferentiated cells and ectopic expression of Oct-4 (and several other transcription factors) can induce pluripotency in differentiated cells. |
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