| Cat.No.: | EAb-1872 |
| Antibody Type: | Polyclonal |
| Immunogen: | This antibody was raised against a peptide within the N-terminal region of human PBRM1. |
| Host: | Rabbit |
| Isotype: | IgG |
| Molecular Weight: | 180 kDa |
| Purification: | Affinity Purified |
| Appearance: | Liquid |
| Formulation: | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. |
| Applications: | ChIP-Seq: 7 µl (4 µg) per ChIP; WB: 1:500 - 1:1,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | PBRM1 (polybromo 1) is a component of the SWI/SNF-B (PBAF) ATP-dependent chromatin-remodeling complex. It is involved in transcriptional activation and repression of select genes by chromatin remodeling and is an integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Defects in PBRM1 have been associated with primary clear cell renal cell carcinoma. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0114 | Human PBRM1 Knockout Cell Line 8bp deletion | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-1119 | Recombinant Zebrafish PBRM1L | Inquiry |
| PE-1695 | PB1 (BD4), His-tag | Inquiry |
| PE-1717 | PB1 (BD6), His-tag | Inquiry |
| ◆ Antibodies | ||
| EAb-1869 | PBX2 Monoclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| PB1 | PBI | PBRM1 | PBRM1L |
| PBX | PBX1b | PBX2 | |
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