| Cat.No.: | EAb-1819 |
| Antibody Type: | Polyclonal |
| Immunogen: | This Sox2 antibody was raised against a peptide within the C-terminal region of human Sox2. |
| Host: | Rabbit |
| Isotype: | IgG |
| Molecular Weight: | 42 kDa |
| Purification: | Affinity Purified |
| Appearance: | Liquid |
| Formulation: | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. |
| Applications: | ChIP: 10 µl per ChIP; ChIP-Seq: 10 µl each; ICC/IF: 1:200 dilution; WB: 1:500 - 1:1,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | Sox2 (SRY related HMG BOX gene 2) is a DNA binding transcription factor and a member of the SOX family of proteins. SOX proteins have an HMG box that binds DNA. Sox2 forms a complex with Oct-4 and controls the expression of a number of genes involved in embryonic. Sox2 is critical for early embryogenesis and for embryonic stem cell pluripotency and thus can serve as a stem cell marker. Overexpression of Sox2 (along with Oct-4, KLF4 and c-Myc) can transform mouse fibroblasts into a state resembling embryonic stem cells (ES cells), referred to as Induced Pluripotency. Defects in Sox2 are the cause of microphthalmia syndromic type 3. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0090 | Recombinant Human SOD3 293 Cell Lysate | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0730 | Recombinant Human SOD3 | Inquiry |
| PE-0731 | Recombinant Human SOD3 | Inquiry |
| PE-0732 | Recombinant Human SOD3, GST-tagged | Inquiry |
| PE-0733 | Recombinant Mouse SOD3 Protein | Inquiry |
| Related Gene / Proteins | |||
| SOD1 | SOD2 | SOD3 | Sox11 |
| Sox2 | Sox6 | ||
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