| Cat.No.: | EAb-1415 |
| Product Name: | DCUN1D1 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Conjugate: | Unconjugated |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Protein G Purified |
| Appearance: | Liquid |
| Formulation: | 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4. |
| Applications: | ELISA, IHC |
| Recommended Dilutions/Conditions: |
ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Alternative Name: | DCUN1 domain-containing protein 1, Defective in cullin neddylation protein 1-like protein 1, Squamous cell carcinoma-related oncogene, DCUN1L1, RP42, SCCRO, DCUN1D1 |
| Scientific Background: | Part of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the cullin component. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0405 | Human DCLRE1C Knockout Cell Line 4bp deletion | Inquiry |
| ◆ Antibodies | ||
| EAb-1406 | DCUN1D2 Polyclonal Antibody, HRP Conjugated | Inquiry |
| EAb-1408 | DCUN1D2 Polyclonal Antibody, Biotin Conjugated | Inquiry |
| EAb-1409 | DCUN1D2 Polyclonal Antibody, FITC Conjugated | Inquiry |
| EAb-1410 | DCUN1D1 Polyclonal Antibody, HRP Conjugated | Inquiry |
| Related Gene / Proteins | |||
| DCAF4 | DCLRE1C | Dcp2 | DCTD |
| DCUN1D1 | DCUN1D2 | ||
USA
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