| Cat.No.: | EAb-0920 |
| Antibody Type: | Polyclonal |
| Conjugate: | Unconjugated |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Affinity Purified |
| Appearance: | Liquid |
| Applications: | ChIP, IP, WB |
| Recommended Dilutions/Conditions: |
WB, IP, ChIP; Recommended dilution: WB 1:500 - 1:2000, IP 1:50 - 1:200, ChIP 1:20 - 1:100 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Alternative Name: | FLJ23414 antibody, H3 K9 HMTase 2 antibody, Histone H3 K9 methyltransferase 2 antibody, Histone lysine N methyltransferase H3 lysine 9 specific 2 antibody, Histone lysine N methyltransferase SUV39H2 antibody, KMT1B antibody, Lysine N methyltransferase 1B antibody, Suppressor of variegation 3 9 homolog 2 (Drosophila) antibody, Su(var)3 9 Drosophila homolog of 2 antibody, Suppressor of variegation 3 9 homolog 2 antibody, Suv39h2 antibody, SUV92_HUMAN antibody |
| Scientific Background: | SUV39H2 encodes a H3 HMTase that shares 59% identity with SUV39H1, but which differs by the presence of a highly basic N terminus. SUV39H2 is also responsible for creating HP1 binding sites in heterochromatin by methylation of histone H3-Lys9. Moreover, SUV39H2 specifically accumulates with chromatin of the sex chromosomes (XYbody), which undergo transcriptional silencing during the first meiotic prophas. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0020 | Suz12 Polyclonal Antibody | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0100 | Chaetocin | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0103 | Recombinant Human SUZ12 293 Cell Lysate | Inquiry |
| EL-0132 | Recombinant Human SUV39H1 293 Cell Lysate | Inquiry |
| EL-0137 | Recombinant Human SUV420H1 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| SUDS3 | SUMO | SUMO1 | SUMO2 |
| SUMO3 | SUN1 | Surf6 | suv39h1 |
| SUV39H2 | SUV3L1 | SUV420H1 | SUV420H2 |
| SUZ12 | |||
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