| Cat.No.: | EAb-0486 |
| Product Name: | Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | The immunogen recognized by this antibody maps to a region between residue 475 and 525 of human Jumonji Domain Containing 2C using the numbering given in entry NP_055876.2 |
| Host: | Rabbit |
| Isotype: | IgG |
| Antibody Target: | KDM4C |
| Purification: | Immunogen affinity purified |
| Appearance: | Liquid |
| Formulation: | Tris-Citrate/Phosphate (pH 7.0 - 8.0) |
| Applications: | WB, ChIP, IP |
| Recommended Dilutions/Conditions: |
Western Blot 1:2000-1:10000; Chromatin Immunoprecipitation 1:10-1:500; Immunoprecipitation 2-5 ug/mg lysate Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Storage Buffer: | 0.09% Sodium Azide |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Alternative Name: | EC 1.14.11; EC 1.14.11.-; GASC-1 protein; GASC1; GASC1JmjC domain-containing histone demethylation protein 3C; Gene amplified in squamous cell carcinoma 1 protein; JHDM3C; JMJD2C; JMJD2CbA146B14.1; jumonji domain containing 2C; Jumonji domain-containing protein 2C; KDM4C; KIAA0780FLJ25949; Lysine (K)specific Demethylase 4C; Lysine (K)-specific Demethylase 4C; lysine-specific demethylase 4C |
| Scientific Background: | This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0015 | Human KDM5B Knockout Cell Line 14bp deletion | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
| ◆ Antibodies | ||
| EAb-0071 | KDM1B Polyclonal Antibody | Inquiry |
| EAb-0072 | JMJD6 Polyclonal Antibody | Inquiry |
| EAb-0074 | JMJD2c Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| JMJD | JMJD1A | JMJD1B | JMJD1C |
| JMJD2 | JMJD2A | JMJD2B | JMJD2C |
| JMJD2D | JMJD2E | JMJD2F | JMJD3 |
| JMJD4 | JMJD5 | JMJD6 | KDM1 |
| KDM1A | KDM1B | KDM2 | KDM2A More > |
| KDM2B | KDM3A | KDM3B | KDM4 |
| KDM4A | KDM4B | KDM4C | KDM4D |
| KDM4E | KDM5 | KDM5A | KDM5B |
| KDM5C | KDM5D | KDM6A | KDM6B |
| KDM6C | KDM7 | KDM7A | KDM7B |
| KDM8 | |||
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