| Cat.No.: | EAb-0370 |
| Antibody Type: | Polyclonal |
| Immunogen: | Synthetic peptide of human ADPRHL2 |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Affinity purification |
| Appearance: | Liquid |
| Applications: | WB, ELISA |
| Recommended Dilutions/Conditions: |
WB: 1:200-1:1000 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse |
| Storage: | -20°C |
| Storage Buffer: | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q9NX46 |
| Alternative Name: | [Protein ADP ribosylarginine] hydrolase like protein 2,[Protein ADP-ribosylarginine] hydrolase-like protein 2,ADP ribosylhydrolase 3,ADP ribosylhydrolase like 2,ADP-ribosylhydrolase 3,Adprhl2,AI836109,ARH3,ARHL2,ecto ADP ribosylhydrolase,FLJ20446,OTTMUSP00000009757,Poly(ADP ribose) glycohydrolase ARH3,Poly(ADP-ribose) glycohydrolase ARH3,Protein ADP ribosylarginine hydrolase like protein 2,RP23-113P22.3 |
| Scientific Background: | This gene encodes a member of the ADP-ribosylglycohydrolase family. The encoded enzyme catalyzes the removal of ADP-ribose from ADP-ribosylated proteins. This enzyme localizes to the mitochondria, in addition to the nucleus and cytoplasm. Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. Poly(ADP-ribose) metabolism may be required for maintenance of the normal function of neuronal cells. Generates ADP-ribose from poly-(ADP-ribose), but does not hydrolyze ADP-ribose-arginine, -cysteine, -diphthamide, or -asparagine bonds. Due to catalytic inactivity of PARG mitochondrial isoforms, ARH3 is the only PAR hydrolyzing enzyme in mitochondria. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0203 | ADNP Polyclonal Antibody | Inquiry |
| EAb-0370 | ADPRHL2 Polyclonal Antibody | Inquiry |
| ◆ Research Kits | ||
| EKIT-0580 | ADMA direct (mouse/rat) ELISA kit | Inquiry |
| EKIT-0581 | ADMA (human) ELISA kit | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-2174 | Recombinant Human ADAL protein (denatured) | Inquiry |
| Related Gene / Proteins | |||
| ADA | ADAL | ADAR1 | ADMA |
| ADNP | ADPRH | ADPRHL2 | |
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