| Cat.No.: | EAb-0326 |
| Product Name: | PIM1 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | Recombinant protein of human PIM1 |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Affinity purification |
| Appearance: | Liquid |
| Applications: | IHC, ELISA |
| Recommended Dilutions/Conditions: |
IHC 1:25-1:100 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse, Rat |
| Storage: | -20°C |
| Storage Buffer: | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | P11309 |
| Alternative Name: | Oncogene PIM 1,Oncogene PIM1,PIM 1,pim 1 kinase 44 kDa isoform,Pim 1 kinase,pim 1 oncogene (proviral integration site 1),Pim 1 oncogene,PIM,PIM1,pim1 kinase 44 kDa isoform,PIM1,Pim2,PIM3,Proto oncogene serine/threonine protein kinase Pim 1,Proto-oncogene serine/threonine-protein kinase Pim-1,Proviral integration site 1,Proviral integration site 2 |
| Scientific Background: | The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0053 | PIM1 Polyclonal Antibody | Inquiry |
| EAb-0326 | PIM1 Polyclonal Antibody | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0200 | Quercetin, Dihydrate | Inquiry |
| BSM-0223 | SMI-4a | Inquiry |
| BSM-0271 | CUDC-907 | Inquiry |
| Related Gene / Proteins | |||
| PI3K | PIAS2 | PIAS4 | PIASy |
| PID | PIM | PIM1 | PIM1 |
| PIM2 | PITX2 | PiwiL2 | PIWIL4 |
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