| Cat.No.: | EAb-0271 |
| Antibody Type: | Polyclonal |
| Immunogen: | Human recombinant SET7/9 amino acids 1-366 |
| Host: | rabbit |
| Appearance: | Liquid |
| Formulation: | 400 µg of protein A-purified antibody |
| Applications: | WB |
| Species Reactivity: | Human, Mouse |
| Shipping: | Wet ice |
| Storage: | -20°C |
| Storage Buffer: | PBS, pH 7.2, with 50% glycerol and 0.02% sodium azide |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q8WTS6 |
| Alternative Name: | KMT7;SETD7/9;SET Domain-Containing Protein 7/9 |
| Scientific Background: | Diverse signal transduction pathways impinging on the N-terminal tails of histones lead to a number of post-translational modifications including acetylation, phosphorylation, poly (ADP-ribosylation), ubiquitination, and methylation. These modifications play critical roles in regulating chromatin structure and gene expression. Histone methyltransferases selectively methylate evolutionarily conserved arginine or lysine residues, primarily in the N-terminal tails of histones H3 and H4. SET7/9 utilizes S-adenosylmethionine to methylate histone H3 at lysine 4. Human SET7/9 is a 366 amino acid protein with observed migration on SDS-PAGE at 49 kDa. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
| ◆ Antibodies | ||
| EAb-0030 | SETD8 Polyclonal Antibody | Inquiry |
| EAb-0031 | SETDB1 Polyclonal Antibody | Inquiry |
| EAb-0032 | Setd1a Polyclonal Antibody | Inquiry |
| EAb-0033 | Setd1b Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| SENP3 | SENP8 | SET | SET1 |
| SET2 | SET7 | SET8 | SET9 |
| SETBP1 | SETD1A | SETD1B | SETD2 |
| SETD3 | SETD5 | SETD6 | SETD7 |
| SETD8 | SETD9 | SetDB1 | SETDB2 More > |
| SETMAR | |||
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