| Cat.No.: | EAb-0233 |
| Product Name: | PRMT1 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | Synthetic peptide corresponding to a portion of human PRMT1. |
| Host: | Rabbit |
| Purification: | Protein G affinity purified. |
| Appearance: | Liquid |
| Formulation: | In PBS containing 0.09% sodium azide. |
| Applications: | ELISA, IHC, WB |
| Recommended Dilutions/Conditions: |
ELISA (1:1,000)Immunohistochemistry (1:50-1:100)Western Blot (1:100-1:500). Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Shipping: | Blue Ice |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q99873 |
| Alternative Name: | SKB, PRDM1 |
| Scientific Background: | Protein arginine N-methyltransferases (PRMTs) catalyze the transfer of a methyl group from S-adenosylmethionine (AdoMet) to a guanidine nitrogen of arginine. PRMT1 methylates arginine residues in glycine-rich areas of histone H4 as well as many non-histone substrates that regulate transcriptional activation, mRNA processing, and signal transduction. In contrast, PRMT5 methylates arginines in proline-, glycine-, methionine-rich motifs and is known to interact with Jak kinases. PRMT2 inhibits NF-κB-dependent transcription and promotes apoptosis. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
| BSM-0047 | SGC707 | Inquiry |
| ◆ Antibodies | ||
| EAb-0048 | PRMT6 Polyclonal Antibody | Inquiry |
| EAb-0049 | PRMT7 Polyclonal Antibody | Inquiry |
| EAb-0050 | PRMT1 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| Pr-SET7 | PRC1 | PRC2 | PRDM1 |
| PRDM10 | PRDM11 | PRDM12 | PRDM13 |
| PRDM14 | PRDM15 | PRDM16 | PRDM17 |
| PRDM2 | PRDM3 | PRDM4 | PRDM5 |
| PRDM6 | PRDM7 | PRDM8 | PRDM9 More > |
| PREP1 | PRIM2 | PRKAA2 | PRKCA |
| PRKCB | PRKCE | PRKDC | PRKRIP1 |
| PRMT | prmt1 | PRMT2 | PRMT3 |
| PRMT5 | prmt6 | PRMT7 | PRMT8 |
| PRMT9 | Progerin | Protamine 2 | Prox1 |
| PRPF31 | PRPF40A | PRSS12 | PRSS55 |
| PRTFDC1 | |||
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