| Cat.No.: | EAb-0213 |
| Product Name: | AROS (human) Polyclonal Antibody (AT135) |
| Antibody Type: | Polyclonal |
| Immunogen: | Recombinant human AROS (aa 2-136). |
| Host: | Rabbit |
| Purification: | Purified from rabbit serum. Protein A-affinity purified. |
| Appearance: | Liquid |
| Formulation: | In PBS containing 0.02% sodium azide. |
| Applications: | WB |
| Recommended Dilutions/Conditions: |
Western blot (1:1,000). Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Shipping: | Blue Ice |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q86WX3 |
| Alternative Name: | Active regulator of SIRT1 |
| Scientific Background: | SIRT1 is a member of the silent information regulator 2 (Sir2) family. It is an NAD+-dependent deacetylase protein that functions in cell death / survival, senescence, and endocrine signaling. It is also involved in the increase of life span following caloric restriction. Recently, the first direct activator of SIRT1 has been described: AROS (active regulator of SIRT1). This nuclear protein of 142 amino acids interacts with SIRT1 and enhances SIRT1-mediated deacetylation of p53. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0001 | Human ARHGEF1 Knockout Cell Line 8bp deletion | Inquiry |
| CL-0002 | Human ARHGEF15 Knockout Cell Line | Inquiry |
| CL-0003 | Human ARHGEF11 Knockout Cell Line | Inquiry |
| CL-0004 | Human ARHGEF10L Knockout Cell Line | Inquiry |
| CL-0005 | Human ARHGEF12 Knockout Cell Line | Inquiry |
| Related Gene / Proteins | |||
| ARD1A | ARF1 | ARHGEF1 | ARHGEF10 |
| ARHGEF10L | ARHGEF11 | ARHGEF12 | ARHGEF15 |
| ARHGEF16 | ARHGEF17 | ARHGEF18 | ARHGEF19 |
| ARID1A | ARID1B | ARID2 | ARID3A |
| ARID4A | ARID5A | ARID5B | ARIH2 More > |
| AROS | ARTD10 | ||
USA
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