5-Hydroxymethyluridine Polyclonal Antibody

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Cat.No.:  EAb-0209
Product Overview:  Goat polyclonal to detect 5-Hydroxymethyluridine
Antibody Type:  Polyclonal
Immunogen:  5-hydroxymethyluridine
Host:  Goat
Isotype:  IgG
Specificity:  Recognizes 5-hydroxymethyluridine.
Purification:  Whole antiserum
Appearance:  Liquid
Formulation:  0.1% Sodium azide
Applications:  IP, ELISA
Recommended Dilutions/Conditions:  ELISA (1:25,000).
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Species independent
Shipping:  Blue Ice
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  5 HmdU antibody/5 Hydroxymethyl 2’ deoxyuridine antibody
Scientific Background:  5-Hydroxymethyluridine antibody recognizes 5-hydroxymethyluridine, which is created by the oxidation of thymine by ionising radiation or reactive oxygen species. This oxidation causes changes in gene expression, mutations, and chromosomal instability all of which play a role in cancer, autoimmune disease and aging. 5-hydroxymethyluridine is a potential biomarker for female breast, colon and rectal cancers, being present at elevated levels, possibly due to impaired DNA repair mechanisms.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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