| Cat.No.: | EAb-0177 |
| Product Name: | SETMAR Polyclonal Antibody |
| Product Overview: | Polyclonal antibody to detect endogenous levels of SETMAR in human, mouse and rat. |
| Antibody Type: | Polyclonal |
| Immunogen: | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human SETMAR |
| Host: | Rabbit |
| Isotype: | IgG |
| Antibody Target: | SETMAR |
| Purification: | Affinity purified |
| Appearance: | Colorless liquid |
| Formulation: | In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide |
| Applications: | WB, IH |
| Recommended Dilutions/Conditions: |
WB; 1:500 – 1:2000, IHC; 1:50 – 1:200 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Positive Control: | WB: NIH3T3, PC12; IHC: lung cancer tissue |
| Species Reactivity: | Human, Mouse, Rat |
| Shipping: | Gel Pack |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q53H47 |
| Alternative Name: | Histone-lysine N-methyltransferase SETMAR; SET domain and mariner transposase fusion gene-containing protein; HsMar1; Metnase |
| Scientific Background: | Protein derived from the fusion of a methylase with the transposase of an Hsmar1 transposon that plays a role in DNA double-strand break repair, stalled replication fork restart and DNA integration. DNA-binding protein, it is indirectly recruited to sites of DNA damage through protein-protein interactions. Has also kept a sequence-specific DNA-binding activity recognizing the 19-mer core of the 5'-terminal inverted repeats (TIRs) of the Hsmar1 element and displays a DNA nicking and end joining activity |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
| ◆ Antibodies | ||
| EAb-0030 | SETD8 Polyclonal Antibody | Inquiry |
| EAb-0031 | SETDB1 Polyclonal Antibody | Inquiry |
| EAb-0032 | Setd1a Polyclonal Antibody | Inquiry |
| EAb-0033 | Setd1b Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| SENP3 | SENP8 | SET | SET1 |
| SET2 | SET7 | SET8 | SET9 |
| SETBP1 | SETD1A | SETD1B | SETD2 |
| SETD3 | SETD5 | SETD6 | SETD7 |
| SETD8 | SETD9 | SetDB1 | SETDB2 More > |
| SETMAR | |||
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