| Cat.No.: | EAb-0058 |
| Product Name: | PHC2 Polyclonal Antibody |
| Product Overview: | Polyclonal Antibody to detect PHC2 in mouse samples. |
| Antibody Type: | Polyclonal |
| Immunogen: | Polyclonal antibody raised in rabbit against mouse PHC2 (polyhomeotic homolog 2) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein. |
| Host: | Rabbit |
| Isotype: | IgG |
| Antibody Target: | PHC2 |
| Purification: | Whole Anti-Sera |
| Appearance: | Colorless liquid |
| Formulation: | In PBS with 0.05% (W/V) sodium azide. |
| Applications: | ELISA. |
| Recommended Dilutions/Conditions: |
ELISA: 1:500. Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Positive Control: | ELISA: Peptides. |
| Species Reactivity: | Mouse |
| Shipping: | Gel Pack |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q8IXK0 |
| Alternative Name: | EDR2, HPH2, PH2 |
| Scientific Background: | PHC2 is a component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. The PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of lysine 119 on histone H2A, rendering chromatin heritably changed in its expressibility. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0056 | PHF8 Polyclonal Antibody | Inquiry |
| EAb-0058 | PHC2 Polyclonal Antibody | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0114 | DMOG | Inquiry |
| ◆ Cell Lines | ||
| CL-0115 | Human PHF6 Knockout Cell Line 1bp deletion | Inquiry |
| CL-0116 | Human PHIP Knockout Cell Line 2bp deletion | Inquiry |
| Related Gene / Proteins | |||
| PHB | PHC1 | PHC2 | PHD |
| PHD1 | PHD2 | PHD3 | PHF1 |
| PHF10 | PHF13 | PHF17 | PHF2 |
| PHF20 | PHF20B | PHF21A | PHF21B |
| PHF6 | PHF8 | PHIP | PHPT1 |
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