| Cat.No.: | EAb-0057 |
| Product Overview: | Polyclonal antibody to detect endogenous levels of ANAPC1 (pS688) in human and mouse. |
| Antibody Type: | Polyclonal |
| Immunogen: | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ANAPC1 |
| Host: | Rabbit |
| Isotype: | IgG |
| Antibody Target: | ANAPC1 |
| Purification: | Affinity purified |
| Appearance: | Colorless liquid |
| Formulation: | In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide |
| Applications: | WB, IH, IF/IC |
| Recommended Dilutions/Conditions: |
WB; 1:500 – 1:2000, IHC; 1:50 – 1:200, IF/IC; 1:50 – 1:100 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Positive Control: | WB: HEK293; IHC: human breast cancer tissue; IFC: HEK293 cells |
| Species Reactivity: | Human, Mouse |
| Shipping: | Gel Pack |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q9H1A4 |
| Alternative Name: | TSG24, Anaphase-promoting complex subunit 1, APC1, Cyclosome subunit 1, Mitotic checkpoint regulator, Testis-specific gene 24 protein |
| Scientific Background: | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0057 | Phospho-ANAPC1 (Ser688) Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0131 | Recombinant Human ANKRD1 293 Cell Lysate | Inquiry |
| EL-0228 | Recombinant Human ANKRA2 293 Cell Lysate | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-1023 | Recombinant Human Ankyrin Repeat Domain 1 (Cardiac Muscle), His-tagged | Inquiry |
| PE-1024 | Recombinant Human ANKRD1, GST-tagged | Inquiry |
| Related Gene / Proteins | |||
| ANAPC1 | Androgen Receptor | ANKRA2 | ANKRD1 |
| ANKRD17 | ANO9A | ||
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