| Cat.No.: | EAb-0028 |
| Product Name: | SIRT2 Polyclonal Antibody |
| Product Overview: | Polyclonal antibody to detect Sirtuin-2 in human, mouse and rat samples |
| Antibody Type: | Polyclonal |
| Immunogen: | Recombinant human Sirtuin 2 |
| Host: | Rabbit |
| Isotype: | IgG |
| Antibody Target: | Sirtuin 2 |
| Specificity: | Recognizes native and recombinant SIRT2. |
| Purification: | Affinity purified antibody |
| Appearance: | Colorless liquid |
| Formulation: | 0.5 mg/ml in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin. |
| Applications: | Western blot |
| Recommended Dilutions/Conditions: |
Western blotting (0.5-4 µg/ml), Immunohistochemistry (20-30 µg/ml) Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Positive Control: | Western Blot: Rat brain lysate |
| Species Reactivity: | Human, mouse, rat |
| Shipping: | Gel Pack |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q8IXJ6 |
| Alternative Name: | Sirtuin 2, Regulatory protein SIR2 homolog 2, SIR2-like protein 2 |
| Scientific Background: | Human sirtuins function as intracellular regulatory proteins. Sirtuin 2 is a member of the class III histone deacetylases (HDACs) and has been implicated in many cellular processes that include histone deacetylation, gene silencing, chromosomal stability, and aging. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0016 | Recombinant Human SIRT1 Lysate | Inquiry |
| EL-0017 | Recombinant Human SIRT2 293 Cell Lysate | Inquiry |
| EL-0018 | Recombinant Human SIRT3 293 Cell Lysate | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0017 | Fluorogenic Sirtuin 5 Substrate | Inquiry |
| SP-0018 | Fluorogenic Sirtuin 6 Substrate | Inquiry |
| Related Gene / Proteins | |||
| Siah2 | SIK1 | SIMC1 | SIN3A |
| SIN3B | SIP1 | Sir2p | SIRT |
| SIRT1 | SIRT2 | SIRT3 | SIRT4 |
| SIRT5 | sirt6 | SIRT7 | SIX3 |
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