| Cat.No.: | EL-0156 |
| Description: | The complex repair response elicited by DNA double-strand breaks (DSBs) includes recruitment of several DNA repair proteins and ubiquitination of H2A-type histones (see MIM 142720). RNF168 is an E3 ubiquitin ligase critical for DSB repair (Stewart et al., 2009 [PubMed 19203578]). |
| Species: | Human |
| Warning: | For research use only, not for diagnostic or therapeutic use. |
| Gene ID NCBI: | 165918 |
| Official Symbol: | RNF168 |
| Official Full Name: | ring finger protein 168, E3 ubiquitin protein ligase |
| Synonyms: | RNF168; ring finger protein 168, E3 ubiquitin protein ligase; ring finger protein 168; E3 ubiquitin-protein ligase RNF168; FLJ35794; FLJ39749; |
| mRNA Refseq: | NM_152617 |
| Protein Refseq: | NP_689830 |
| MIM: | 612688 |
| UniProt ID: | Q8IYW5 |
| Chromosome Location: | 3q29 |
| Function: | chromatin binding; histone binding; ligase activity; metal ion binding; protein binding; ubiquitin binding; ubiquitin-protein ligase activity; zinc ion binding; |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0123 | Human RNF167 Knockout Cell Line | Inquiry |
| CL-0124 | Human RNF2 Knockout Cell Line 553bp insertion | Inquiry |
| CL-0125 | Human RNF25 Knockout Cell Line | Inquiry |
| CL-0126 | Human RNF26 Knockout Cell Line | Inquiry |
| CL-0127 | Human RNF24 Knockout Cell Line | Inquiry |
| Related Gene / Proteins | |||
| RNA Helicase A | RNA pol II | RNF103 | RNF11 |
| RNF128 | RNF133 | RNF138 | RNF141 |
| RNF167 | RNF168 | RNF181 | RNF182 |
| RNF183 | RNF2 | RNF20 | RNF207 |
| RNF208 | RNF212 | RNF213 | RNF214 More > |
| RNF215 | RNF217 | RNF219 | RNF220 |
| RNF222 | RNF223 | RNF224 | RNF24 |
| RNF25 | RNF26 | RNF31 | RNF40 |
| RNF7 | RNF8 | RNP | RNPC3 |
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