| Cat.No.: | BSM-0405 |
| Product Name: | Butein |
| CAS No.: | 487-52-5 |
| Figure: |
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| Synonyms: | 2',3,4,4'-Tetrahydroxychalcone |
| Description: | Plant polyphenol. Specific tyrosine kinase inhibitor. Potently inhibits the tyrosine kinase activity of the EGF receptor and p60c-src. Potent antioxidant and anti-inflammatory agent. Inhibits glutathione reductase and rat liver glutathione S-transferase. Activator of human deacetylase SIRT1. Inhibits aromatase, showing chemopreventive properties. Directly inhibits IKK. |
| Appearance: | Yellow solid. |
| Molecular Weight: | 272.3 |
| Purity: | ≥98% (HPLC) |
| Storage: | -20°C |
| Targets: | SIRT1 |
| Molecular Formula: | C15H12O5 |
| Solubility: | DMSO (>50mg/ml) or methanol; insoluble in water. |
| Handling: | Keep cool and dry under inert gas. Protect from light. |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0016 | Recombinant Human SIRT1 Lysate | Inquiry |
| EL-0017 | Recombinant Human SIRT2 293 Cell Lysate | Inquiry |
| EL-0018 | Recombinant Human SIRT3 293 Cell Lysate | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0017 | Fluorogenic Sirtuin 5 Substrate | Inquiry |
| SP-0018 | Fluorogenic Sirtuin 6 Substrate | Inquiry |
| Related Gene / Proteins | |||
| Siah2 | SIK1 | SIMC1 | SIN3A |
| SIN3B | SIP1 | Sir2p | SIRT |
| SIRT1 | SIRT2 | SIRT3 | SIRT4 |
| SIRT5 | sirt6 | SIRT7 | SIX3 |
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