| Cat.No.: | BSM-0354 |
| Product Name: | CPTH6 (hydrobromide) |
| Figure: |
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| Product Overview: | A Gcn5 and pCAF HAT inhibitor |
| Description: | CPTH6 is a thiazole derivative that inhibits the lysine acetyltransferase activity of Gcn5 and pCAF but not p300 or CBP. It blocks the acetylation of H3/H4 histones and α-tubulin in several leukemia cell lines. CPTH6 reduces cell viability, arresting cell cycling in the G0/G1 phase and inducing apoptosis. It impairs autophagy in a variety of tumor cell lines, at least in part by altering ATG7-mediated elongation of autophagosomal membranes. |
| Appearance: | A crystalline solid |
| Molecular Weight: | 386.7 |
| Purity: | ≥98% |
| Storage: | -20°C |
| Targets: | Gcn5 and pCAF HAT |
| Molecular Formula: | C15H16ClN3S • HBr |
| Chemical Name: | 3-methyl-2-[4-(4-chlorophenyl)-2-thiazolyl]hydrazone, cyclopentanone, hydrobromide |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0037 | CPTH2 | Inquiry |
| BSM-0039 | Embelin | Inquiry |
| BSM-0108 | Curcumin, Curcuma longa (High Purity) | Inquiry |
| ◆ Antibodies | ||
| EAb-0060 | PCAF Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0106 | Recombinant Human PCNA Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| GCN5 | PCAF | PCBP2 | PCBP3 |
| PCBP4 | PCGF2 | PCGF6 | PCL2 |
| PCNA | |||
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