| Cat.No.: | BSM-0341 |
| CAS No.: | 1982372-88-2 |
| Figure: |
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| Product Overview: | A selective inhibitor of SUV420H1 and SUV420H2 |
| Description: | A-196 is a selective inhibitor of SUV420H1 and SUV420H2 (IC50s = 25 and 144 nM, respectively) that is more than 100-fold selective over other histone methyltransferases and non-epigenetic targets. A-196 has been shown to inhibit the di- and tri-methylation of lysine 20 of histone H4 (H4K20me) in multiple cell lines with IC50 values less than 1 μM. |
| Appearance: | A crystalline solid |
| Molecular Weight: | 359.3 |
| Purity: | ≥98% |
| Storage: | -20°C |
| Targets: | SUV420H1 and SUV420H2 |
| Molecular Formula: | C18H16Cl2N4 |
| Chemical Name: | 6,7-dichloro-N-cyclopentyl-4-(4-pyridinyl)-1-phthalazinamine |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0020 | Suz12 Polyclonal Antibody | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0100 | Chaetocin | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0103 | Recombinant Human SUZ12 293 Cell Lysate | Inquiry |
| EL-0132 | Recombinant Human SUV39H1 293 Cell Lysate | Inquiry |
| EL-0137 | Recombinant Human SUV420H1 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| SUDS3 | SUMO | SUMO1 | SUMO2 |
| SUMO3 | SUN1 | Surf6 | suv39h1 |
| SUV39H2 | SUV3L1 | SUV420H1 | SUV420H2 |
| SUZ12 | |||
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