| Cat.No.: | BSM-0316 |
| Product Name: | TZ9 |
| CAS No.: | 1002789-86-7 |
| Figure: |
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| Product Overview: | A Rad6B inhibitor |
| Description: | TZ9 is a cell-permeable triazine compound that inhibits the human E2 ubiquitin-conjugating enzyme Rad6B. TZ9 selectively docks to the Rad6B catalytic site, inhibits Rad6B-induced histone H2A ubiquitination, downregulates intracellular β-catenin, induces G2/M arrest and apoptosis, and inhibits proliferation and migration of metastatic human breast cancer cells (IC50 = 6 µM). |
| Appearance: | A crystalline solid |
| Molecular Weight: | 366.3 |
| Purity: | ≥98% |
| Storage: | -20°C |
| Targets: | Rad6B |
| Molecular Formula: | C17H14N6O4 |
| Chemical Name: | 4-amino-6-(phenylamino)-2-(4-nitrobenzoate)-1,3,5-triazine-2-methanol |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0044 | RARA Polyclonal Antibody | Inquiry |
| EAb-0356 | RAD54L2 Polyclonal Antibody | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0316 | TZ9 | Inquiry |
| ◆ Cell Lines | ||
| CL-0390 | Human RAD52 Knockout Cell Line 2bp insertion | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-1231 | Recombinant Human RAC3, His-tagged | Inquiry |
| Related Gene / Proteins | |||
| RAC3 | Rad21 | RAD52 | RAD54L2 |
| Rad6 | Rad6B | RAG1 | RAG2 |
| RALY | RALYL | RANBP2 | RAP1 |
| RAR-β | RAR-γ | RARA | |
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